DENV-IN-12

• UNSPSC Description:

  DENV-IN-12 (Compound 6) is a derivative of N-methylcytisine thio, which inhibits DENV-1 and DENV-2. DENV-IN-12 displays robust antiviral activity against DENV-2, with EC50 values ranging from 0.002 to 0.005 μM in different cell lines[1].

• Target Antigen:

  Dengue virus

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/denv-in-12.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C=CC=C([C@@H]2C3)N1C[C@@H]3CN(C)C2=S

• Molecular Weight:

  234.32

• References & Citations:

  [1]Lin CS, et al. Inhibition of dengue viruses by N-methylcytisine thio derivatives through targeting viral envelope protein and NS2B-NS3 protease. Bioorg Med Chem Lett. 2024 Jan 18;99:129623.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2581065-80-5