DENV-IN-12

DENV-IN-12

• CAS Number: 2581065-80-5
• UNSPSC Description: DENV-IN-12 (Compound 6) is a derivative of N-methylcytisine thio, which inhibits DENV-1 and DENV-2. DENV-IN-12 displays robust antiviral activity against DENV-2, with EC50 values ranging from 0.002 to 0.005 μM in different cell lines[1].
• Target Antigen: Dengue virus
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/denv-in-12.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C=CC=C([C@@H]2C3)N1C[C@@H]3CN(C)C2=S
• Molecular Weight: 234.32
• References & Citations: [1]Lin CS, et al. Inhibition of dengue viruses by N-methylcytisine thio derivatives through targeting viral envelope protein and NS2B-NS3 protease. Bioorg Med Chem Lett. 2024 Jan 18;99:129623.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported