DENV-IN-6
CAT:
804-HY-143273
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DENV-IN-6
- CAS Number: 2375780-95-1
- UNSPSC Description: DENV-IN-6 is a potent DENV (I-IV) inhibitor with EC50s of 17.5, 13.20, 6.8 and 11.41 μM for the inhibition of DENV (I-IV) replication, respectively. DENV-IN-6 also exhibits activity of anti-HIV-1IIIB (EC50=0.0181 μM; CC50=64.92 μM)[1].
- Target Antigen: DNA/RNA Synthesis; HIV
- Type: Reference compound
- Related Pathways: Anti-infection;Cell Cycle/DNA Damage
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/denv-in-6.html
- Solubility: 10 mM in DMSO
- Smiles: CCC1=C(N=C(NC1=O)SCC2=NNC(C3=CC=C(C=C3)F)=C2Cl)CC4CCCCC4
- Molecular Weight: 461.00
- References & Citations: [1]Rui RM, et al. C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity. Bioorg Chem. 2022 Feb;119:105494.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported