DENV-IN-2

DENV-IN-2

• CAS Number: 2253675-62-4
• UNSPSC Description: DENV-IN-2 is a potent dengue viral replication inhibitor extracted from patent WO2018215315A1, compound 6AB, has an EC50 of 0.016 nM. DENV-IN-2 shows high potent activity against all four serotypes of the Dengue virus with EC50s ranging from 0.013 to 0.029 nM[1].
• Target Antigen: Dengue virus; DNA/RNA Synthesis; Flavivirus
• Type: Reference compound
• Related Pathways: Anti-infection;Cell Cycle/DNA Damage
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/denv-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@H]1[C@H](COC2=CC(OC)=CC(N[C@@H](C3=CC=C(Cl)C=C3)C(N4CCC5=C4C=C(OC(F)(F)F)C=C5)=O)=C2)C1)O
• Molecular Weight: 590.97
• References & Citations: [1]Jean-François BONFANTI, et al.Substituted indoline derivatives as dengue viral replication inhibitors. WO2018215315A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported