SDH-IN-11

• Description :

  SDH-IN-11 (compound A7) is a SDH inhibitor, and shows inhibitory effect on nematode feeding, reproductive ability, and egg hatching. SDH-IN-11 promotes the oxidative stress of nematodes and causes intestinal damage to nematodes. SDH-IN-11 inhibits the activity of succinate dehydrogenase (SDH) in nematodes[1].

• CAS Number :

  [2998946-58-8]

• UNSPSC :

  12352005

• Target :

  Fungal

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/sdh-in-11.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NCC1=NOC(C2=CC=C(C(F)(F)F)C=C2Cl)=N1)C3=C(C(F)(F)F)C=CC=C3

• Molecular Formula :

  C18H10ClF6N3O2

• Molecular Weight :

  449.73

• References & Citations :

  [1]Wang Y, et al. Design, Synthesis, Nematicidal Activity, and Mechanism of Novel Amide Derivatives Containing an 1,2,4-Oxadiazole Moiety. J Agric Food Chem. 2024;72 (1) :128-139.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported