Cbl-b-IN-10

Cbl-b-IN-10

• CAS Number: 2815225-12-6
• UNSPSC Description: Cbl-b-IN-10 (Compound 463) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.0 nM and 3.5 nM, respectively[1].
• Target Antigen: E1/E2/E3 Enzyme
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cbl-b-in-10.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=CC(CNC3(CCC3)C)=CC(C(F)(F)F)=C2CN1C4=CC(NCC)=CC(C5(CCC5)CC6=NN=CN6C)=C4
• Molecular Weight: 566.66
• References & Citations: [1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported