Cbl-b-IN-6

Cbl-b-IN-6

• CAS Number: 2815221-33-9
• UNSPSC Description: Cbl-b-IN-6 (Compound 246) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.7 nM and 5.2 nM, respectively[1].
• Target Antigen: E1/E2/E3 Enzyme
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cbl-b-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: FC(F)(C1)CC1(C2=CC(N3CC4=C(C(F)(F)F)C=C([C@H](C)NC5(CCC5)C)C=C4C3=O)=CC=C2)CC6=NN=CN6C
• Molecular Weight: 573.60
• References & Citations: [1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported