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Cbl-b-IN-6

CAT: 0804-HY-156762Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156762Size:1 Each
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Description
Cbl-b-IN-6 (Compound 246) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.7 nM and 5.2 nM, respectively[1].
CAS Number
2815221-33-9
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbl-b-in-6.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1)CC1(C2=CC(N3CC4=C(C(F)(F)F)C=C([C@H](C)NC5(CCC5)C)C=C4C3=O)=CC=C2)CC6=NN=CN6C
Molecular Formula
C30H32F5N5O
Molecular Weight
573.60
References & Citations
[1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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