Anticancer agent 144

• Description:

  Anticancer agent 144 (compound 444) is a dual PTPN2/PTP1B inhibitor with IC50 values [1].

• UNSPSC:

  12352005

• Target:

  Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-144.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=P(O)(C(F)(C1=C(Br)C2=C(C(OCC3=CC=C(S(=O)(C)=O)C=C3)=CC(C4=NN=CN4)=C2)S1)F)O

• Molecular Formula:

  C19H15BrF2N3O6PS2

• Molecular Weight:

  594.34

• References & Citations:

  [1]David A CANDITO, et al. Substituted benzothiophene derivatives and methods of use thereof. Patent WO2023121939A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2948340-59-6]