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Pan-KRAS-IN-3

CAT: 0804-HY-156555Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156555Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pan-KRAS-IN-3 (Example 84) is a pan-KRAS inhibitor. pan-KRAS-IN-3 can be used for research of cancers[1]. pan-KRAS-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
2875116-29-1
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pan-kras-in-3.html
Solubility
10 mM in DMSO
Smiles
FC1=C(C2=CC(O)=CC3=C2C(C#C)=C(F)C=C3)N=CC4=C1N=C(N=C4N5CCCCCC5)OC[C@@]67N(CCC7)C[C@@H](C6)F
Molecular Formula
C33H32F3N5O2
Molecular Weight
587.63
References & Citations
[1]Leon M. Smith Ii, et al. Tetraline, phenylcyclobutane, and phenylcyclopentane analogs as rxfp1 agonists. Patent. WO2023114819A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras

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