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Pan-KRAS-IN-4

CAT: 0931-T79799-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79799-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2885961-55-5
Target
Ras
Related Pathways
GPCR/G Protein, MAPK
Bioactivity
Pan-KRAS-IN-4 (compound 5) is a potent KRAS inhibitor, demonstrating IC50 values of 0.37 nM for Kras G12C and 0.19 nM for Kras G12V [1].
Smiles
C(#C)C=1C=2C(=CC(O)=CC2C=CC1F)C3=C(F)C4=C(C=N3)C(=NC(OCC56N(CCC5)CCC6)=N4)N7CC8N(C(C=C)=O)C(C7)CC8
Molecular Formula
C36H34F2N6O3
Molecular Weight
636.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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