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ROCK-IN-8

CAT: 0804-HY-156550Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156550Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ROCK-IN-8 (Example 4) is a ROCK inhibitor, with an IC50 value less than 100 nM. ROCK-IN-8 has anti-inflammatory activity. ROCK-IN-8 can be used for research of respiratory and gastro-intestinal diseases[1].
CAS Number
1621103-79-4
UNSPSC
12352005
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rock-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C1OCCC1SC2=CC=C(C(NC3=CC(C4=CC(C(NC5=C(F)C=NC=C5)=O)=CC=C4CN)=CC=C3)=O)C=C2
Molecular Formula
C30H25FN4O4S
Molecular Weight
556.61
References & Citations
[1]Sandro Boland, et al. Pyridine derivatives as soft rock inhibitors. Patent. WO2014118133.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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