ROCK-IN-4

• Target:

  Others|||ROCK

• Related Pathways:

  Cytoskeletal Signaling|||Others|||Cell Cycle/Checkpoint|||Stem Cells

• Bioactivity:

  ROCK-IN-4 is a potent ROCK inhibitor that maintains NO release capacity, reversibly depolymerizes F-actin, and blocks mitochondrial respiration in human trabecular meshwork (HTM) cells. ROCK-IN-4 can be utilized to study glaucoma or high intraocular pressure.

• Smiles:

  Cl.C[C@H]1CN(CCCN1S(=O)(=O)c1cccc2cncc(F)c12)C(=O)OCCCCO[N+]([O-])=O

• Molecular Formula:

  C20H26ClFN4O7S

• Molecular Weight:

  520.96

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2488395-07-7