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ROCK-IN-32

CAT: 0804-HY-113641Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-113641Size:1 Each
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Description
ROCK-IN-32 is a ROCK inhibitor, with an IC50 value of 11 nM for ROCK2. ROCK-IN-32 can be used in research of cardiovascular disease, cancer and inflammation[1].
CAS Number
1013117-40-2
UNSPSC
12352005
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rock-in-32.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C=C1)[C@H]2CNC[C@@H]2C(NC3=CC4=C(C=C3Cl)C(NC=C4)=O)=O
Molecular Formula
C20H17Cl2N3O2
Molecular Weight
402.27
References & Citations
[1]Bosanac T, et al. Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines. Bioorg Med Chem Lett. 2010 Jun 15;20 (12) :3746-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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