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Anti-inflammatory agent 60

CAT: 0804-HY-156398Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156398Size:1 Each
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Description
Anti-inflammatory agent 60 (compound 21) inhibitsnitric oxide production, with anIC50value of 12.95 μM.Anti-inflammatory agent 60reducesiNOS, phosphorylated p65, andβ-cateninexpression in a concentration-dependent manner[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
NF-κB; NO Synthase; β-catenin
Type
Reference compound
Related Pathways
Immunology/Inflammation; NF-κB; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-60.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C1=CC(C(C)(C)C)=CC(CCC2=CC(O)=CC(O)=C2)=C1)C
Molecular Formula
C22H30O2
Molecular Weight
326.47
References & Citations
[1]Lei M, et al. Design, Synthesis, anti-inflammatory activity Evaluation, preliminary exploration of the Mechanism, molecule Docking, and structure-activity relationship analysis of batatasin III analogs [published online ahead of print, 2023 Oct 16]. Bioorg Med Chem Lett. 2023;96:129527.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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