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Anti-inflammatory agent 50

CAT: 0804-HY-155753Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155753Size:1 Each
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Description
Anti-inflammatory agent 50 (compound a1) is a Fusidic acid derivative with anti-inflammatory effects. Anti-inflammatory agent 50 inhibits inflammatory factor NO, IL-6 and TNF-α. Anti-inflammatory agent 50 alleviates acute lung injury by regulating inflammatory mediators and suppressing the MAPK, NF-κB and NLRP3 inflammasome signaling pathways[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
COX; NF-κB
Type
Reference compound
Related Pathways
Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-50.html
Solubility
10 mM in DMSO
Smiles
C/C(C)=C\CC/C(C(OCC1=CN(C2=CC=CC=C2)N=N1)=O)=C3[C@@H](OC(C)=O)C[C@]4(C)[C@@]5(C)CC[C@@]6([H])[C@H](C)[C@H](O)CC[C@]6(C)C5[C@H](O)C[C@@]/34[H]
Molecular Formula
C40H55N3O6
Molecular Weight
673.88
References & Citations
[1]Zheng Liu, et al. Design, synthesis fusidic acid derivatives alleviate acute lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway. Eur J Med Chem. 2023 Aug 1;259:115697.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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