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Anti-inflammatory agent 65

CAT: 0931-T83047-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T83047-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3035442-58-8
Target
STING, NO Synthase
Related Pathways
Immunology/Inflammation
Bioactivity
Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation of IRF3 and p65, and disrupting the STING/IRF3/NF-κB signaling pathway, thus attenuating the inflammatory response [1].
Smiles
O=C([C@]1([C@@]2([H])CC(C)(C)CC1)CC[C@]3(C)C2=CC[C@@]([C@](CCC([C@]4(COC(CCCNC(CCCC[C@H]5SSCC5)=O)=O)C)=O)(C)[C@@]4([H])CC6)([H])[C@]36C)OCC7=CC=CC=C7
Molecular Formula
C49H71NO6S2
Molecular Weight
834.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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