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Anti-inflammatory agent 17

CAT: 0804-HY-146547Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146547Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-inflammatory agent 17 is a potent and orally active anti-inflammatory agent. Anti-inflammatory agent 17 inhibits the release of IL-6 and TNF-α in vitro experiments without cytotoxicity. Anti-inflammatory agent 17 exhibits anti-inflammatory activity in vivo. Anti-inflammatory agent 17 has the potential for the research of Acute lung injury (ALI) [1].
CAS Number
2763226-84-0
UNSPSC
12352005
Target
Interleukin Related; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-17.html
Solubility
10 mM in DMSO
Smiles
CN(CCCOC1=CC=C(C(C(/C=C/C2=CC(O)=C(C=C2)O)=O)=C1)O)C
Molecular Formula
C20H23NO5
Molecular Weight
357.40
References & Citations
[1]Wang X, et al. Design, synthesis and bioactivity evaluation of fisetin derivatives as potential anti-inflammatory agents against LPS-induced acute lung injury. Bioorg Med Chem. 2021; 49:116456.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-6; TNFRSF5/CD40