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Laxiflorin B-4

CAT: 0804-HY-156394Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156394Size:1 Each
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Description
Laxiflorin B-4 is modificative compound of Laxiflorin B , exhibited higher affinity for ERK1/2 and stronger tumor suppression[1].
CAS Number
2810956-32-0
UNSPSC
12352005
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/laxiflorin-b-4.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@](C2[C@@]3(C[C@@H](CC2)C4=C)C4=O)([C@@H](C(C)(C=C1)C)COC(C5=CN(N=C5)C6=CC=CN=C6)=O)COC3=O
Molecular Formula
C29H29N3O6
Molecular Weight
515.56
References & Citations
[1]Cheng-Yao Chiang, et al. A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer. Acta Pharmacol Sin. 2023 Oct 10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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