Laxiflorin B

CAT: 0804-HY-156393Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-156393Size:1 Each
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Description
Laxiflorin B, a herbal compound, is a novel selective ERK1/2 inhibitor that has antitumor activity[1].
CAS Number
[165337-71-3]
UNSPSC
12352005
Target
ERK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/laxiflorin-b.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@]2(COC([C@]3(C4=O)[C@@]2([H])CC[C@@H](C4=C)C3)=O)[C@H](CO)C(C)(C)C=C1
Molecular Formula
C20H24O5
Molecular Weight
344.40
References & Citations
[1]Cheng-Yao Chiang, et al. A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer. Acta Pharmacol Sin. 2023 Oct 10.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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