Laxiflorin B

Laxiflorin B

• CAS Number: 165337-71-3
• UNSPSC Description: Laxiflorin B, a herbal compound, is a novel selective ERK1/2 inhibitor that has antitumor activity[1].
• Target Antigen: ERK
• Type: Natural Products
• Related Pathways: MAPK/ERK Pathway;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/laxiflorin-b.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1[C@]2(COC([C@]3(C4=O)[C@@]2([H])CC[C@@H](C4=C)C3)=O)[C@H](CO)C(C)(C)C=C1
• Molecular Weight: 344.40
• References & Citations: [1]Cheng-Yao Chiang, et al. A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer. Acta Pharmacol Sin. 2023 Oct 10.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported