SDH-IN-9

• Description:

  SDH-IN-9 (compound Ip) is a potent inhibitor of Succinate Dehydrogenase. SDH-IN-9 shows fungicidal activity against Fusarium graminearum Schw with the EC50 of 0.93 μg/mL[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sdh-in-9.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CN(C)N=C1C(F)F)N(C(C)CSC2=NC3=C(F)C=C(F)C=C3S2)OC

• Molecular Formula:

  C17H16F4N4O2S2

• Molecular Weight:

  448.46

• References & Citations:

  [1]Yin YM, et al. Discovery of Benzothiazolylpyrazole-4-Carboxamides as Potent Succinate Dehydrogenase Inhibitors through Active Fragment Exchange and Link Approach. J Agric Food Chem. 2023;71 (40) :14471-14482.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported