Anticancer agent 160

• Description :

  Anticancer agent 160 (Compound 6) is a natural product derived from Parthenium hysterophorus. Anticancer agent 160 is cytotoxic to HCT-116 cells, IC50=5.0 μM[1].

• CAS Number :

  [2983122-03-6]

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Natural Products

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-160.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C=C[C@]2(O)[C@]1(C)[C@H](OC([C@]3(C(C(C4=CC=CC=C45)=O)6C5=O)C[C@@H]7N6CCC7)=O)[C@H]3CC[C@@H]2C

• Molecular Formula :

  C28H29NO6

• Molecular Weight :

  475.53

• References & Citations :

  [1]Singh CP, et al. Semisynthesis of Novel Dispiro-pyrrolizidino/thiopyrrolizidino-oxindolo/indanedione Natural Product Hybrids of Parthenin Followed by Their Cytotoxicity Evaluation. ACS Omega. 2023 Sep 14;8 (38) :35283-35294.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Caspase 3