8304-vs

8304-vs

• UNSPSC Description: 8304-vs is a macrocyclic anti-Plasmodial agent that covalently and irreversibly targets the Plasmodium proteasome. 8304-vs effectively inhibits the growth of Plasmodium falciparum[1].
• Target Antigen: Parasite; Proteasome
• Type: Reference compound
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/8304-vs.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N(CCC1)[C@@H](CC2=CC(OCCCC[C@H](N3)C(N[C@H](/C=C/S(C)(=O)=O)CC(C)C)=O)=CC=C2)C(N[C@H](C3=O)CCN4CCOCC4)=O
• Molecular Weight: 703.89
• References & Citations: [1]Bennett JM, et al. Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum. ACS Infect Dis. 2023 Sep 15..
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported