VS-15

• Description:

  VS-15, a IDO1 inhibitor, selectively binds the heme-free form of IDO1. VS-15 is described as an iNOS inhibitor based on the reduction of NO production[1].

• UNSPSC:

  12352005

• Target:

  Indoleamine 2,3-Dioxygenase (IDO) ; NO Synthase

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/vs-15.html

• Smiles:

  O=C(NCCC1=CNC2=C1C=CC=C2)C3=C(NC(C(NCCC4=CNC5=C4C=CC=C5)=O)=O)C=CC=C3

• Molecular Formula:

  C29H27N5O3

• Molecular Weight:

  493.56

• References & Citations:

  [1]Eleonora Panfili, et al. Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1. ACS Pharmacol Transl Sci. 2024 Sep 12;7 (10) :3056-3070.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 4

• CAS Number:

  [951948-78-0]