Z-Pro-Pro-CHO

CAT: 0804-HY-134454-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-134454-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Z-Pro-Pro-CHO is a prolyl oligopeptidase inhibitor (IC50: 0.16 μM and 0.01 μM for human and Schistosoma Mansoni prolyl oligopeptidase respectively) [1].

CAS Number

108708-25-4

UNSPSC

12352209

Target

Parasite; Prolyl Endopeptidase (PREP)

Type

Peptides

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/z-pro-pro-cho.html

Purity

98.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1C(C(N2C(C=O)CCC2)=O)CCC1)OCC3=CC=CC=C3

Molecular Formula

C18H22N2O4

Molecular Weight

330.38

References & Citations

[1]Fajtová P, et al. Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors. PLoS Negl Trop Dis. 2015 Jun 3;9 (6) :e0003827.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

Schistosome

Chemical Information

Z-Pro-Pro-CHO

See also: N-Benzyloxycarbonylprolylprolinal (annotation moved to); Z-Pro-Prolinal (annotation moved to).

CAS Number	108708-25-4
PubChem CID	4350
IUPAC Name	benzyl 2-(2-formylpyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate
Molecular Formula	C18H22N2O4
Molecular Weight	330.4
XLogP	1.7
Topological Polar Surface Area	66.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Heavy Atom Count	24
Formal Charge	0
Complexity	476

SMILES

C1CC(N(C1)C(=O)C2CCCN2C(=O)OCC3=CC=CC=C3)C=O

InChI

InChI=1S/C18H22N2O4/c21-12-15-8-4-10-19(15)17(22)16-9-5-11-20(16)18(23)24-13-14-6-2-1-3-7-14/h1-3,6-7,12,15-16H,4-5,8-11,13H2

InChIKey

ORZXYSPOAVJYRU-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 108708-25-4

CID: 4350

Formula: C18H22N2O4

MW: 330.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	330.4
XLogP3	1.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	330.15795719
Monoisotopic Mass	330.15795719
Topological Polar Surface Area	66.9 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	476
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-P10007	Z-Gly-Pro-Phe-Leu-CHO
HY-P4612-01	Z-Pro-Pro
HY-P4611	Z-Pro-Ala
HY-134454A	Z-Pro-prolinal
HY-P4308	Z-Pro-Pro-aldehyde-dimethyl acetal
HY-D1670-01	Z-Gly-Pro-AMC
HY-137220-01	Z-Gly-Pro-pNA
HY-P4498	Z-Ala-Pro-pNA
HY-76317-01	Z-DL-Pro-OH
HY-P2718	Z-Gly-Pro-Gly-Gly-Pro-Ala-OH

Alternative Products

Catalog	Name
T78619-01	Z-Pro-Pro-CHO
BML-ZW9490-0100	Z-Pro-Nle-Asp-CHO
C-2545.0025	Z-Pro-Pro-OH
MBS5822389	Z-Gly-Pro-Phe-Leu-CHO
FP111060-01	Z-Pro-Pro-aldehyde-dimethyl acetal
SGP-3029-01	Z-Gly-Pro-Leu-Gly-Pro
C-2475.0025	Z-Pro-OSu
4001343.0025	Z-Pro-OH
NDA79532-01	Z-Pro-prolinal
5-07436	Z-Pro-NH2

Z-Pro-Pro-CHO

Chemical Information

Related Products

Alternative Products

Popular Products