Sirtuin modulator 6

CAT: 0804-HY-155988-03Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-155988-03Size:10 mg

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Description

Sirtuin modulator 6 (compound 262) increases the lifespan of a cell. Sirtuin modulator 6 can be used for study of diabetes, obesity, neurodegenerative diseases, cardiovascular disease, and so an extracted from patent WO2009064913A1[1].

CAS Number

476633-98-4

UNSPSC

12352005

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sirtuin-modulator-6.html

Purity

99.70

Solubility

DMSO : 12.62 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC=C(C=C1OC)OC)NC2=CC=C(C3=NC4=C(N3)C=CC=C4)C=C2

Molecular Formula

C22H19N3O3

Molecular Weight

373.40

References & Citations

[1]Joseph J, et al. Benzimidazole derivatives as sirtuin modulators. WO2007019416A1. 2011.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Chemical Information

N-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-2,4-dimethoxybenzamide

CAS Number	476633-98-4
PubChem CID	4384381
IUPAC Name	N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide
Molecular Formula	C22H19N3O3
Molecular Weight	373.4
XLogP	3.9
Topological Polar Surface Area	76.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Heavy Atom Count	28
Formal Charge	0
Complexity	523

SMILES

COC1=CC(=C(C=C1)C(=O)NC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3)OC

InChI

InChI=1S/C22H19N3O3/c1-27-16-11-12-17(20(13-16)28-2)22(26)23-15-9-7-14(8-10-15)21-24-18-5-3-4-6-19(18)25-21/h3-13H,1-2H3,(H,23,26)(H,24,25)

InChIKey

FTPMCWPNLDTGMY-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 476633-98-4

CID: 4384381

Formula: C22H19N3O3

MW: 373.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	373.4
XLogP3	3.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	373.14264148
Monoisotopic Mass	373.14264148
Topological Polar Surface Area	76.2 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	523
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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