Sirtuin modulator 8

• Description:

  Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. Sirtuin modulator 8 significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21) . Sirtuin modulator 8 regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases (such as diabetes, obesity) and inflammatory diseases[1].

• UNSPSC:

  12352005

• Target:

  Sirtuin

• Related Pathways:

  Cell Cycle/DNA Damage; Epigenetics

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Purity:

  96.24

• Smiles:

  O=C(C1=NC2=CC=CC=C2N=C1)NC3=C(C4=CN5C(CN6CCC(CC6)N)=CSC5=N4)C=CC=C3

• Molecular Formula:

  C26H25N7OS

• Molecular Weight:

  483.59

• References & Citations:

  [1]Olivier Boss, et al. Biomarkers of sirtuin activity and methods of use thereof.WO2008115518A2.US.2008-09-25

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [925437-38-3]