Sirtuin modulator 1

• Description :

  Sirtuin modulator 1 is a modulator of SIRTl, a homolog of SIRT3, with EC1.5 of < 1 μM, extracted from patent WO 2010071853 A1, Compound No.4.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Sirtuin

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Sirtuin-modulator-1.html

• Purity :

  99.85

• Solubility :

  DMSO : 12.5 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=C(CCCOC)SC(C2=CC=CC=C2)=N1)NC3=CC=CC=C3C4=NC5=C(N=CC(CN6CCCC6)=C5)S4.Cl[H]

• Molecular Formula :

  C31H32ClN5O2S2

• Molecular Weight :

  606.20

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Thiazolopyridine sirtuin modulating compounds. WO 2010071853 A1

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  SIRT1

• CAS Number :

  [2070015-26-6]