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Boc-MIF-1-Am

CAT: 0804-HY-155466Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155466Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boc-MIF-1-Am (compound 2) is a human dopamine D2 receptor enhancer (EC50=17.82 nM) and is a bioconjugate of melanostatin (MIF-1) and amantadine. Boc-MIF-1-Am (200 μM) exhibited mild neurotoxicity in SH-SY5Y cells[1].
CAS Number
3056144-84-1
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/boc-mif-1-am.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(C)C)C(NCC(NC1(C[C@H](C2)C3)C[C@H]3C[C@H]2C1)=O)=O)[C@H]4N(C(OC(C)(C)C)=O)CCC4
Molecular Formula
C28H46N4O5
Molecular Weight
518.69
References & Citations
[1]Silva-Reis S C et al. Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D2 Receptors[J]. ACS Medicinal Chemistry Letters, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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