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Mag-indo-1/AM

CAT: 0804-HY-D1700Size: 1 EachDry Ice: NoHazardous: No
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Description
Mag-indo-1/AM is a cell-permeable fluorescent indicator for Mg2+ and also for Ca2+ (Ex=340-390 nm, Em=410-490 nm) . Mag-indo-1/AM can be used to determine intracellular Mg2+ and Ca2+ concentrations[1][2].
CAS Number
130926-94-2
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mag-indo-1-am.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=C(C=C1)C=C(C3=CC=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OCC(OCOC(C)=O)=O)=C3)N2)OCOC(C)=O
Molecular Formula
C33H34N2O17
Molecular Weight
730.63
References & Citations
[1]Griffiths EJ. Calcium handling and cell contraction in rat cardiomyocytes depleted of intracellular magnesium. Cardiovasc Res. 2000 Jul;47 (1) :116-23. |[2]Morelle B, et al. Measurement of intracellular magnesium concentration in 3T3 fibroblasts with the fluorescent indicator Mag-indo-1. Anal Biochem. 1994 Apr;218 (1) :170-6.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

Chemical Information

Mag-Indo 1-AM
CAS Number130926-94-2
PubChem CID2762665
IUPAC Nameacetyloxymethyl 2-[4-[bis[2-oxo-2-(2-oxopropoxymethoxy)ethyl]amino]phenyl]-1H-indole-6-carboxylate
Molecular FormulaC30H32N2O12
Molecular Weight612.6
XLogP2.9
Topological Polar Surface Area177
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count13
Rotatable Bond Count21
Heavy Atom Count44
Formal Charge0
Complexity976
SMILES
CC(=O)COCOC(=O)CN(CC(=O)OCOCC(=O)C)C1=CC=C(C=C1)C2=CC3=C(N2)C=C(C=C3)C(=O)OCOC(=O)C
InChI
InChI=1S/C30H32N2O12/c1-19(33)14-39-16-42-28(36)12-32(13-29(37)43-17-40-15-20(2)34)25-8-6-22(7-9-25)26-10-23-4-5-24(11-27(23)31-26)30(38)44-18-41-21(3)35/h4-11,31H,12-18H2,1-3H3
InChIKey
XLQNJLJDRRJLCB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Mag-Indo 1-AM
CAS: 130926-94-2
CID: 2762665
Formula: C30H32N2O12
MW: 612.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight612.6
XLogP32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count13
Rotatable Bond Count21
Exact Mass612.19552446
Monoisotopic Mass612.19552446
Topological Polar Surface Area177 Ų
Heavy Atom Count44
Formal Charge0
Complexity976
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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