Products for Research Use Only
RegisterLogin

TGR5 agonist 4

CAT: 0804-HY-155307Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-155307Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TGR5 agonist 4 (compound 19), a cholic acid derivative, is a selective TGR5 agonist with an EC50 of 4 μM[1].
UNSPSC
12352211
Target
G protein-coupled Bile Acid Receptor 1
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tgr5-agonist-4.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C[C@H]([C@]1(CC[C@]2([C@@]3([C@@H](C[C@@]4(C[C@@H](CC[C@@]4([C@]3(C[C@@H]([C@@]21C)O)[H])C)O)[H])O)[H])[H])[H])C)C(O)=O
Molecular Formula
C24H38F2O5
Molecular Weight
444.55
References & Citations
[1]Emiliano Rosatelli, et al. Chemical exploration of TGR5 functional hot-spots: Synthesis and structure-activity relationships of C7- and C23-Substituted cholic acid derivatives. Eur J Med Chem. 2023 Oct 1:261:115851.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-156830-01TGR5 Receptor Agonist 4
HY-149807TGR5 agonist 1
HY-14229-01TGR5 Receptor Agonist
HY-155306TGR5 agonist 3
HY-168140TGR5 agonist 6
HY-149808TGR5 agonist 2
HY-168329TGR5 agonist 7
HY-161817TGR5 agonist 5
HY-156830A-01(4′R) -TGR5 Receptor Agonist 4
HY-146453TGR5 Receptor Agonist 3

Alternative Products

CatalogName
B1185-5TGR5 Receptor Agonist
T203565-01TGR5 agonist 7
T200705-01TGR5 agonist 6
SD2384-5mgTGR5 (GPCR19 agonist)
GTR19220890-01TGR5 agonist 1
GTR19218689-01TGR5 agonist 3
GTR19274766-01TGR5 agonist 9
T74825-01TGR5 agonist 2
B1635-25TGR5-Receptor-Agonist
GTR19231323-01TGR5 agonist 4

Popular Products