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SHP2-IN-32

CAT: 0804-HY-169111Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169111Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHP2-IN-32 (compound C6) is an orally active, allosteric SHP2 inhibitor with an IC50 value of 0.13 nM. SHP2-IN-32 exhibits antitumor activity[1].
CAS Number
3043685-80-6
UNSPSC
12352005
Target
SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shp2-in-32.html
Smiles
N[C@@H]1C2=C(C=CC=C2)CC13CCN(C4=NC=C(SC5=C(Cl)C(NC(C6=C(O)C=CN=C6)=O)=CC=C5)N=C4)CC3
Molecular Formula
C29H27ClN6O2S
Molecular Weight
559.08
References & Citations
[1]Lv X, et al. Discovery of novel substituted pyridine carboxamide derivatives as potent allosteric SHP2 inhibitors. Eur J Med Chem. 2024 Sep 5;279:116830.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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