SHP2-IN-32

SHP2-IN-32

• CAS Number: 3043685-80-6
• UNSPSC Description: SHP2-IN-32 (compound C6) is an orally active, allosteric SHP2 inhibitor with an IC50 value of 0.13 nM. SHP2-IN-32 exhibits antitumor activity[1].
• Target Antigen: SHP2
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/shp2-in-32.html
• Smiles: N[C@@H]1C2=C(C=CC=C2)CC13CCN(C4=NC=C(SC5=C(Cl)C(NC(C6=C(O)C=CN=C6)=O)=CC=C5)N=C4)CC3
• Molecular Weight: 559.08
• References & Citations: [1]Lv X, et al. Discovery of novel substituted pyridine carboxamide derivatives as potent allosteric SHP2 inhibitors. Eur J Med Chem. 2024 Sep 5;279:116830.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported