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Antimycobacterial agent-6

CAT: 0804-HY-155059Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155059Size:1 Each
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Description
Antimycobacterial agent-6 (compound 25) is a potent inhibitor of Mycobacterium tuberculosis (Mtb), targeting to both wild-type and fluoroquinolone-resistant Mtb strains. Antimycobacterial agent-6 inhibits Mtb DprE1-C387S mutant with MIC90s of 0.9 μM (H37Rv), 0.9 μM (MoxR), 0.5 μM (DprE1-P116S), respectively[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimycobacterial-agent-6.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCC1=CC=C(C(F)(F)F)C=C1)C2CNC3=C([N+]([O-])=O)C=C(C(F)(F)F)C=C3C2=O
Molecular Formula
C20H15F6N3O4
Molecular Weight
475.34
References & Citations
[1]Dube PS, et al. Quinolone analogues of benzothiazinone: Synthesis, antitubercular structure-activity relationship and ADME profiling. Eur J Med Chem. 2023 Oct 5;258:115539.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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