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Antimycobacterial agent-2

CAT: 0804-HY-147704Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147704Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antimycobacterial agent-2 (compound 58) is a potent antimycobacterial agent. Antimycobacterial agent-2 shows anti-mycobacterial activities with an MIC99 of 0.8 µM for Mycobacterium tuberculosis (M.tb) H37Rv. Antimycobacterial agent-2 shows cytotoxic activities with an IC50 of48.1 µM for CHO cells[1].
CAS Number
62670-49-9
UNSPSC
12352211
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimycobacterial-agent-2.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]12CC[C@]3([C@@]([C@@H](C[C@]4(/C([C@H](C[C@]34C)OCC)=C(C(O)=O)\CC/C=C(C)\C)[H])O)([C@]1(CC[C@H]([C@H]2C)O)C)[H])C
Molecular Formula
C31H50O5
Molecular Weight
502.73
References & Citations
[1]Singh K, et al. Structure-activity relationship analyses of fusidic acid derivatives highlight crucial role of the C-21 carboxylic acid moiety to its anti-mycobacterial activity. Bioorg Med Chem. 2020 Jul 1;28 (13) :115530.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported