PCSK9-IN-19

PCSK9-IN-19

• UNSPSC Description: PCSK9-IN-19 (Compound 1) is a PCSK9 inhibitor. PCSK9-IN-19 can be used for research of high LDL-cholesterol levels and prevention of coronary artery disease[1].
• Target Antigen: PCSK9
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/pcsk9-in-19.html
• Solubility: 10 mM in DMSO
• Smiles: C[N+](CCOCCOCCC(NC[C@H](NC(CCSCC1=CC(CSCCNC2=O)=CC3=C1)=O)C(N[C@H](C)C(N[C@H](C(N[C@@H]4CC5=CN(CC6=CN3N=N6)C7=C5C=C(F)C=C7)=O)CC8=CC(C/C=C/CO[C@H]([C@@]9([H])C(N[C@H](C(N[C@H](C(N%10CCC[C@]%102C)=O)CC%11=CC=C(OC)C=C%11)=O)[C@H](O)C)=O)CC[N@@]9C4=O)=CC=C8)=O)=O)=O)(C)C.[Cl-]
• Molecular Weight: 1647.37
• References & Citations: [1]Kuethe JT, et al. Synthesis of a Complex and Highly Potent PCSK9 Inhibitor. Org Lett. 2023 Jul 14;25(27):5001-5005.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported