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PCSK9-IN-19

CAT: 0804-HY-155006Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155006Size:1 Each
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Description
PCSK9-IN-19 (Compound 1) is a PCSK9 inhibitor. PCSK9-IN-19 can be used for research of high LDL-cholesterol levels and prevention of coronary artery disease[1].
UNSPSC
12352005
Target
PCSK9
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pcsk9-in-19.html
Solubility
10 mM in DMSO
Smiles
C[N+](CCOCCOCCC(NC[C@H](NC(CCSCC1=CC(CSCCNC2=O)=CC3=C1)=O)C(N[C@H](C)C(N[C@H](C(N[C@@H]4CC5=CN(CC6=CN3N=N6)C7=C5C=C(F)C=C7)=O)CC8=CC(C/C=C/CO[C@H]([C@@]9([H])C(N[C@H](C(N[C@H](C(N%10CCC[C@]%102C)=O)CC%11=CC=C(OC)C=C%11)=O)[C@H](O)C)=O)CC[N@@]9C4=O)=CC=C8)=O)=O)=O)(C)C.[Cl-]
Molecular Formula
C81H105ClFN15O15S2
Molecular Weight
1647.37
References & Citations
[1]Kuethe JT, et al. Synthesis of a Complex and Highly Potent PCSK9 Inhibitor. Org Lett. 2023 Jul 14;25 (27) :5001-5005.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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