2’-Deoxy-2’-fluoro-4’-thio-a-D-arabinouridine

• UNSPSC Description:

  2’-Deoxy-2’-fluoro-4’-thio-a-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-deoxy-2-fluoro-4-thio-a-d-arabinouridine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  F[C@H]1[C@H](O)[C@@H](CO)S[C@@H]1N2C=CC(NC2=O)=O

• Molecular Weight:

  262.26

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported