2′-Deoxy-2′-fluoro-3-deaza-arabinouridine

2′-Deoxy-2′-fluoro-3-deaza-arabinouridine

• CAS Number: 2095417-48-2
• UNSPSC Description: 2′-Deoxy-2′-fluoro-3-deaza-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/2-deoxy-2-fluoro-3-deaza-arabinouridine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@H](F)[C@H](N2C=CC(O)=CC2=O)O[C@@H]1CO
• Molecular Weight: 245.20
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported