5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine

5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine

• CAS Number: 69123-97-3
• UNSPSC Description: 5-Bromo-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-bromo-2-deoxy-2-fluoro-β-d-arabinouridine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@H](F)[C@@H](O[C@@H]1CO)N(C(N2)=O)C=C(Br)C2=O
• Molecular Weight: 325.09
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported