2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine

2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine

• CAS Number: 892145-76-5
• UNSPSC Description: 2’-Deoxy-2’-fluoro-4-thio-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/2-deoxy-2-fluoro-4-thio-beta-d-arabinouridine.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H]1[C@@H](O)[C@H](F)[C@H](N2C(NC(C=C2)=S)=O)O1
• Molecular Weight: 262.26
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported