4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine

4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine

• CAS Number: 173379-73-2
• UNSPSC Description: 4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1]. 4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/4-azido-2-deoxy-2-fluoro-beta-d-arabinouridine.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@]1(N=[N+]=[N-])[C@@H](O)[C@H](F)[C@H](N2C(NC(C=C2)=O)=O)O1
• Molecular Weight: 287.20
• References & Citations: [1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported