Rev 2’-O-MOE-C(Bz)-5’-amidite

CAT:

804-HY-154230

Size:

Inquire

Price:

Ask

UNSPSC Description:
Rev 2’-O-MOE-C(Bz)-5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen:
Nucleoside Antimetabolite/Analog
Type:
Oligonucleotides
Related Pathways:
Cell Cycle/DNA Damage
Applications:
Cancer-programmed cell death
Field of Research:
Cancer
Assay Protocol:
https://www.medchemexpress.com/rev-2-o-moe-c-bz-5-amidite.html
Solubility:
10 mM in DMSO
Smiles:
O=C1N=C(NC(C2=CC=CC=C2)=O)C=CN1[C@@H]3O[C@@H]([C@H]([C@H]3OCCOC)OC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)COP(N(C(C)C)C(C)C)OCCC#N
Molecular Weight:
907.99
References & Citations:
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions:
Room temperature
Clinical Information:
No Development Reported

Related Products

CAT	Name
HY-154230	Rev 2’-O-MOE-C(Bz)-5’-amidite
HY-154261	Rev 2’-O-MOE-A(Bz)-5’-amidite
HY-154442	Rev 2’-O-MOE-5MeC(Bz)-5’-amidite
HY-W570890-01	2'-O-MOE-5-Me-C(Bz)
HY-154258	Rev 2’-O-MOE-5MeU-5’-amidite
HY-154259	Rev 2’-O-MOE-G(iBu)-5’-amidite
HY-154546	3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite
HY-104017-01	DMT-2'-O-MOE-rA(Bz) phosphoramidite
HY-154064	3’-O-MOE-A(Bz)-2’-CED-phosphoramidite
HY-154443	Rev dC(Bz)-5'-amidite

CAT	Name
MBS5817131	Rev 2'-O-MOE-C(Bz)-5'-amidite
TNU1533-01	Rev 2’-O-MOE-A(Bz)-5’-amidite
MBS5827122	Rev 2'-O-MOE-A(Bz)-5'-amidite
MBS5817135	Rev 2'-O-MOE-A(Bz)-5'-amidite
MBS5817150	Rev 2'-O-MOE-5MeC(Bz)-5'-amidite
MBS5826710	2'-O-MOE-5-Me-C(Bz)
OR1027856-01	2'-O-Moe-5-Me-C (Bz)
TNU1531-01	Rev 2’-O-MOE-C(Bz)-5’-amidite; N4-Benzoyl-3'-O-(4,4’-dimethoxy t
MBS5827119	Rev 2'-O-MOE-G(iBu)-5'-amidite
TNU1530-01	Rev 2’-O-MOE-G(iBu)-5’-amidite