3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite

3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite

• CAS Number: 1098233-10-3
• UNSPSC Description: 3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/3-o-moe-5me-c-bz-2-phosphoramidite.html
• Solubility: 10 mM in DMSO
• Smiles: COC(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)OC[C@H]4O[C@@H](N5C(NC(NC(C6=CC=CC=C6)=O)C(C)=C5)=O)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]4OCCOC
• Molecular Weight: 924.03
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported