DMT-2'-O-MOE-rA(Bz) phosphoramidite

DMT-2'-O-MOE-rA(Bz) phosphoramidite

• CAS Number: 251647-53-7
• UNSPSC Description: DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dmt-2-o-moe-ra-bz-phosphoramidite.html
• Purity: 98.0
• Solubility: DMSO : 200 mg/mL (ultrasonic)
• Smiles: CC(C)N(C(C)C)P(O[C@H]1[C@@H](OCCOC)[C@H](N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O)O[C@@H]1OC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)OCCC#N
• Molecular Weight: 917.98
• References & Citations: [1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, stored under nitrogen)
• Clinical Information: No Development Reported