3’-O-MOE-A(Bz)-2’-CED-phosphoramidite

3’-O-MOE-A(Bz)-2’-CED-phosphoramidite

• CAS Number: 256224-01-8
• UNSPSC Description: 3’-O-MOE-A(Bz)-2’-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/3-o-moe-a-bz-2-ced-phosphoramidite.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=CC=C1)NC2=NC=NC3=C2N=CN3[C@H]4[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H](OCCOC)[C@@H](COC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)O4
• Molecular Weight: 932.01
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported