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Vortioxetine-d8 (hydrobromide)

CAT: 0804-HY-15414AS-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15414AS-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vortioxetine-d8 (Lu AA 21004-d8) hydrobromide is the deuterated form of Vortioxetine. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM) [1].
Product Name Alternative
Lu AA21004-d8 (hydrobromide)
UNSPSC
12352005
Target
5-HT Receptor; Isotope-Labeled Compounds; Serotonin Transporter
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Purity
99.41
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(SC2=CC=CC=C2N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])C(C)=C1.[H]Br
Molecular Formula
C18H15D8BrN2S
Molecular Weight
387.41
References & Citations
[1]Bang-Andersen B, et al. Discovery of 1-[2- (2,4-dimethylphenylsulfanyl) phenyl]piperazine (Lu AA21004) : a novel multimodal compound for the treatment of major depressive disorder. J Med Chem. 2011 May 12;54 (9) :3206-21.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor;5-HT3 Receptor;5-HT7 Receptor

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