Vortioxetine-d8

CAT: 0804-HY-15414SSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15414SSize:1 mg
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Description
Vortioxetine-d8 (Lu AA 21004-d8) is a deuterated version of Vortioxetine. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM) [1].
CAS Number
[2140316-62-5]
Product Name Alternative
Lu AA 21004 D8
UNSPSC
12352005
Target
5-HT Receptor; Isotope-Labeled Compounds; Serotonin Transporter
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(SC2=CC=CC=C2N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])C(C)=C1
Molecular Formula
C18H14D8N2S
Molecular Weight
306.49
References & Citations
[1]Bang-Andersen B, et al. Discovery of 1-[2- (2,4-dimethylphenylsulfanyl) phenyl]piperazine (Lu AA21004) : a novel multimodal compound for the treatment of major depressive disorder. J Med Chem. 2011 May 12;54 (9) :3206-21.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor;5-HT3 Receptor;5-HT7 Receptor

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Alternative Products

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RM-O201604-01Vortioxetine-D8
MBS5767842Vortioxetine D8
sc-475110Vortioxetine Hydrobromide-D8
MF-0102083-01Vortioxetine-d8 2HBr
TRC-N991171-10MGN-Nitroso-Vortioxetine-D8
TRC-V766007-10MGVortioxetine-d8 Sulfoxide Fumarate
TRC-D477797-10MGN’-(2,4-Dimethylphenyl) Vortioxetine-d8
460155N’- (2,4-Dimethylphenyl) Vortioxetine-d8
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