3’-O-MOE-5MeU-2’-phosphoramidite

CAT:

804-HY-154545

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CAS Number: 256223-93-5
UNSPSC Description: 3’-O-MOE-5MeU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/3-o-moe-5meu-2-phosphoramidite.html
Solubility: 10 mM in DMSO
Smiles: COC(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)OC[C@H]4O[C@@H](N5C(NC(C(C)=C5)=O)=O)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]4OCCOC
Molecular Weight: 818.89
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-104016-02	2'-O-MOE-5MeU-3'-phosphoramidite
HY-104016-01	2'-O-MOE-5MeU-3'-phosphoramidite
HY-104016-03	2'-O-MOE-5MeU-3'-phosphoramidite
HY-154545	3’-O-MOE-5MeU-2’-phosphoramidite
HY-154544	3’-O-MOE-U-2’-phosphoramidite
HY-154549	3’-O-MOE-G(iBu)-2’-phosphoramidite
HY-154258	Rev 2’-O-MOE-5MeU-5’-amidite
HY-154546	3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite
HY-154064	3’-O-MOE-A(Bz)-2’-CED-phosphoramidite
HY-104017-03	DMT-2'-O-MOE-rA(Bz) phosphoramidite