5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

CAT:

804-HY-154222

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CAS Number: 142808-44-4
UNSPSC Description: 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/5-o-dmtr-2-2-difluoro-dc-bz-3-ced-phosphoramidite.html
Solubility: 10 mM in DMSO
Smiles: CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C(F)(F)[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
Molecular Weight: 869.89
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-154222	5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite
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HY-W545104-02	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
HY-W545104-03	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
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Cat	Name
TNU1119-5mg	N6-Bz-5’-O-DMTr-3’-deoxyadenosine-2’-O-CED-phosphoramidite
TNU1119-1g	N6-Bz-5’-O-DMTr-3’-deoxyadenosine-2’-O-CED-phosphoramidite
TNU1119-50mg	N6-Bz-5’-O-DMTr-3’-deoxyadenosine-2’-O-CED-phosphoramidite
TNU1119-10mg	N6-Bz-5’-O-DMTr-3’-deoxyadenosine-2’-O-CED-phosphoramidite
TNU1119-1mg	N6-Bz-5’-O-DMTr-3’-deoxyadenosine-2’-O-CED-phosphoramidite
TNU1122-5mg	N6-Bz-5’-O-DMTr-3’-O-methyladenosine-2’-O-CED-phosphoramidite
TNU1122-50mg	N6-Bz-5’-O-DMTr-3’-O-methyladenosine-2’-O-CED-phosphoramidite
TNU1122-1mg	N6-Bz-5’-O-DMTr-3’-O-methyladenosine-2’-O-CED-phosphoramidite
TNU1122-10mg	N6-Bz-5’-O-DMTr-3’-O-methyladenosine-2’-O-CED-phosphoramidite
TNU1122-1g	N6-Bz-5’-O-DMTr-3’-O-methyladenosine-2’-O-CED-phosphoramidite