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PROTAC BRD4 Degrader-20

CAT: 0804-HY-153820Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153820Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC BRD4 Degrader-20 (compound 195) is an bifunctional compound and an degrader of BRD4[1].
CAS Number
2086300-61-8
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-degrader-20.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(N[C@H]4C[C@H](C4)OC5=CC=C(OC(C(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(N[C@H](C7=CC=C(C8=C(N=CS8)C)C=C7)C)=O)=O)=O)=C9)C9=C5)=O)C%10=NN=C(C)N2%10
Molecular Formula
C55H58ClN9O7S2
Molecular Weight
1056.69
References & Citations
[1]Qian Yimin, et al. Preparation of bifunctional PROTAC compounds and methods for the enhanced degradation of targeted bromodomain-containing proteins. World Intellectual Property Organization, WO2017030814 A1. 2017-02-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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