PROTAC BRD4 Degrader-20

• CAS Number:

  2086300-61-8

• UNSPSC Description:

  PROTAC BRD4 Degrader-20 (compound 195) is an bifunctional compound and an degrader of BRD4[1].

• Target Antigen:

  Epigenetic Reader Domain; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-brd4-degrader-20.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(N[C@H]4C[C@H](C4)OC5=CC=C(OC(C(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(N[C@H](C7=CC=C(C8=C(N=CS8)C)C=C7)C)=O)=O)=O)=C9)C9=C5)=O)C%10=NN=C(C)N2%10

• Molecular Weight:

  1056.69

• References & Citations:

  [1]Qian Yimin, et al. Preparation of bifunctional PROTAC compounds and methods for the enhanced degradation of targeted bromodomain-containing proteins. World Intellectual Property Organization, WO2017030814 A1. 2017-02-23.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported