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Hedgehog IN-5

CAT: 0804-HY-153730Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153730Size:1 Each
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Description
Hedgehog IN-5 is an orally active small molecule inhibitor of the hedgehog pathway. Hedgehog IN-5 can be used for the research of fibrotic disease[1].
CAS Number
1544681-93-7
UNSPSC
12352005
Target
Hedgehog
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hedgehog-in-5.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=C(C(NC2=CC(C3=NC=C(C(C)C)N3)=C(C=C2)Cl)=O)C=CC(N4C[C@@H](N([C@@H](C4)C)C)C)=C1)F
Molecular Formula
C27H31ClF3N5O
Molecular Weight
534.02
References & Citations
[1]Cai, Sui Xiong et al. Application of hedgehog pathway inhibitor for treatment of fibrotic diseases. World Intellectual Property Organization, WO2018082587 A1 2018-05-11
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
T86566-01Hedgehog IN-5
bs-60004C-01Hh-Ag1.5 --- Hedgehog Agonist
217423Hhat Inhibitor, RU-SKI 43 (2- (2-Methylbutylamino) -1- (4- (m-tolyloxymethyl) -6,7-dihydrothieno[3,2-c]pyridin-5 (4H) -yl) ethanone, 2- ((2-Methylbutyl) amino) -1- (4- ((3-methylphenoxy) methyl) -6,7-dihydrothieno[3,2-c]pyridin-5 (4H) -yl) ethanone, Hedgehog Acyltransferase Inhibitor, RU-SKI43)
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T200011-01Hedgehog IN-7
T75148-01Hedgehog IN-3
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