Hedgehog IN-9

• Description :

  Hedgehog IN-9 (Compound 1) is a Hedgehog inhibitor. Hedgehog IN-9 prevents GLI1 expression and enhances cellular BRD2 protein levels. Hedgehog IN-9 inhibits growth of medulloblastoma spheroid cells and can be used for synthesis of photoaffinity labeling probe[1].

• UNSPSC :

  12352005

• Target :

  Epigenetic Reader Domain; Gli; Hedgehog

• Related Pathways :

  Epigenetics; Stem Cell/Wnt

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  CCN1C(C2=C3C(C(S(=O)(NC4CCCCC4)=O)=CC=C31)=CC=C2)=O

• Molecular Formula :

  C19H22N2O3S

• Molecular Weight :

  358.45

• References & Citations :

  [1]Tsakoumagkos IA, et al. Evaluation of Benzo[cd]indol-2 (1H) -ones as Downstream Hedgehog Pathway Inhibitors. ChemistryOpen. 2025 Apr 14:e202500119.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [438488-95-0]