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BTK-IN-25

CAT: 0804-HY-153705Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153705Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BTK-IN-25 (Compound 71) is a BTK inhibitor (IC50: 0.77 nM) . BTK-IN-25 inhibits the proliferation of DOHH2 cells (IC50: 1 nM) [1].
CAS Number
2562351-92-0
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-in-25.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C=C(C=C1)OC2=C(C=CC=C2)F)F)C3=CNC4=NC=C(OCC)C(N[C@@H]5CC[C@H](OC5)CO)=C34
Molecular Formula
C28H27F2N3O5
Molecular Weight
523.53
References & Citations
[1]Tan H, et al. Substituted pyrrolo[2,3-b]pyridine and pyrazolo[3,4-b]pyridine derivatives as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cell proliferative disorders. World Intellectual Property Organization, WO2020239124 A1. 2020-12-03.|[2]Tan Haohan. Substituted pyrrolo [2,3-b ] pyridine and pyrazolo [3,4-b ] pyridine derivatives as protein kinase inhibitors. Patent. CN114008042.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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